Peptide synthesis

The facility operates four peptide synthesizers and three HPLC systems for protein and peptide purification:

4 Peptide Synthesizers:

  • 2 x SYRO (MultiSynTech)
  • 1 x Liberty Blue microwave peptide synthesizer, CEM
  • 1 SPOT synthesizer ResPep SL (Intavis Bioanalytical Instruments)

3 HPLCs:

  • 1 x NGC chromatography system (Bio-Rad)
  • 2 x Ultimate 3000 (Thermo Scientific)

Peptide Synthesizers

The picture shows a Syro II peptide synthesizer (MultiSynTech GmbH), which is a fully automatic, computer controlled instrument based on a two arms pipetting robot.

SPOT Synthesizer

The picture shows our SPOT synthesizer ResPep SL from Intavis Bioanalytical Instruments.

Microwave Synthesizer

The picture shows our Liberty Blue microwave peptide synthesizer (CEM, acquired in 2017), which lead to a substantial improvement in purity and length of the synthesized peptides.

HPLCs for peptide and antibody purification

We operate one HPLC (NGC chromatography system, Biorad, see picture) equipped with affinity columns for antibody purifications…
…and two HPLCs (Ultimate 3000 (Thermo Scientific) equipped with reversed phase columns for peptide purification.