M46 - Elyra7 with lattice SIM2

The M46 system is a super-resolution system. It features 3D single molecule localisation SMLM, lattice structure illumination SIM2, SIM2 Apotome, TIRF.  

SMLM with techniques like PALM, dSTORM or PAINT bring lateral resolution down to 20-30nm. The reshaping of PSF brings the axial resolution down to 50-80nm across 1.4um volume 

The lattice SIM pattern allows fast acquisition compared to a classical SIM and the SIM2 reconstruction achieves XY resolution down to 60nm and can be used with standard fluorescent slides and probes. 

Dual camera link and unique image processing algorithms allow fast (simultaneous) two-colour imaging (up to 255fps)